Yann Bissek's first goal in Italy just before half-time at the San Siro and a late finish from Nicolo Barella were enough for Inter to bounce back from cup defeat to Bologna midweek and keep closest challengers Juventus at bay.

Inter's dynamic attacking duo made sure their team took full advantage of closest rivals Juventus only drawing at Genoa on Friday to put daylight between Simone Inzaghi's side and the rest of the chasing pack

Paulo Dybala picked out Lukaku with a clever cross as the Belgium striker headed Roma in front in the fifth minute at the Stadio Olimpico.

Turkey playmaker Hakan Calhanoglu set up a goal and scored another as Inter Milan moved back to the summit of Serie A with Saturday's comfortable 4-0 home win over Udinese.

The centre-back rose highest shortly after the break to nod in the only goal of a closely contested match between two of Italy's footballing powerhouses.

Lautaro Martinez ensured that Inter Milan kept hold of their two-point lead at the top of Serie A as he struck in Sunday's scrappy 1-1 draw at closest rivals Juventus.

AC Milan starlet Francesco Camarda made history on Saturday after becoming the youngest ever player to play in Serie A during Saturday's 1-0 win over Fiorentina.

Mazzarri's team are still seven points behind leaders Inter Milan who travel to Turin on Sunday for the weekend's big match at second-placed Juventus

Inter Milan and Juventus face off on Sunday in a clash between Serie A's two title favourites and historic rivals, as Walter Mazzarri begins his second reign at troubled Napoli.

Napoli continued their struggles on home turf with Sunday's shock 1-0 defeat to Empoli which left the Serie A champions already well off the pace in this season's title race.

Napoli winger Matteo Politano and forward Giacomo Raspadori both scored after the break to cancel out two first-half headers by Olivier Giroud in an energetic game that saw the two teams dominate one half each.

Argentina striker Martinez nodded home his 11th league goal of the season in the 67th minute of a straightforward win in Turin as Inter went one point ahead of AC Milan, who host third-placed Juventus on Sunday night.

Italian club Juventus' midfielder Nicolo Fagioli is under investigation for alleged illegal betting activities, a prosecutor said on Wednesday, confirming earlier press reports.

 Bologna fought back from two goals down to snatch a 2-2 draw with Inter Milan at the San Siro in Serie A on Saturday after early goals from Francesco Acerbi and captain Lautaro Martinez had put the hosts in command.

Lukaku grabbed his third goal in five league games for Roma after latching onto a clever pass from Paulo Dybala midway through the first half.

Inter rebounded from their first loss of the season midweek against Sassuolo thanks to a sensational second-half display from Martinez.

Portugal winger Leao netted his third goal in as many league matches in the eighth minute at a sodden San Siro to move Milan up to second on 12 points from five games

Stefano Pioli insisted on Monday that AC Milan have turned their attentions to the Champions League opener with Newcastle United after the local derby humiliation at the weekend.

Belgium forward Lukaku rolled in Roma's sixth in the 82nd minute of a dominating performance in which talisman Paulo Dybala also got off the mark for the season with a brace.

Inter Milan laid down an early title marker on Saturday by handing out a 5-1 derby hammering to AC Milan and going it alone at the Serie A summit, while champions Napoli were held 2-2 at promoted Genoa.